Chemotherapy-Induced Nausea and Vomiting: Pathogenesis, Recommendations, and New Trends
نویسندگان
چکیده
منابع مشابه
Chemotherapy-induced nausea and vomiting: ESMO clinical recommendations for prophylaxis.
antiemetics 5-Hydroxytryptamine type 3 receptor (5HT3) (serotonin) antagonists, corticosteroids and aprepitant are usually given once daily. However, for delayed emesis corticosteroids are given two times daily. Dopamine antagonists are given three or four times daily. For routine use oral doses are recommended [I, A]. Palonosetron is only available as an i.v. formulation. Substances of the sam...
متن کاملChemotherapy-induced nausea and vomiting.
younger patient age, platinumor anthracyclinebased chemotherapy, low alcohol consumption, earlier cycles of chemotherapy, previous history of morning sickness, and prior emetic episodes after chemotherapy. The acute and delayed scoring systems both had good predictive accuracy when applied to the external validation sample (acute— auroc: 0.69; 95% confidence interval: 0.59 to 0.79; delayed—auro...
متن کاملChemotherapy-induced nausea and vomiting.
Chemotherapy-induced nausea and vomiting (CINV) affects many cancer patients and has a great influence on quality of life. CINV involves coordination of several organs of the gastrointestinal tract, the peripheral and central nervous systems. Many neurotransmitters are involved in this process, and the predominant receptors are serotonin, neurokinin-1 and dopamine receptors. Risk factors for CI...
متن کاملChemotherapy-Induced Nausea and Vomiting
In the past two decades, significant advances have been made in the management of chemotherapy-induced nausea and vomiting (CINV). These advances are primarily due to a greater understanding of the physiological and molecular pathways underlying CINV, which resulted in major progress in the management of patients with CINV. In the early 1990s, CINV treatment consisted of dex-amethasone [1]. Imp...
متن کاملChemotherapy-induced nausea and vomiting.
Nausea and vomiting (N&V) is among the most distressing side effects of chemotherapy, despite the development of more efficacious antiemetic agents. As many as 60% of patients who receive cancer chemotherapy experience some degree of N&V. However, the actual incidence is difficult to determine with accuracy because of the variety of drugs, doses, and health conditions of the patients who receiv...
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ژورنال
عنوان ژورنال: Cancer Treatment and Research Communications
سال: 2021
ISSN: 2468-2942
DOI: 10.1016/j.ctarc.2020.100278